Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7797604 | European Journal of Medicinal Chemistry | 2016 | 37 Pages |
Abstract
The drugs obtained by the combination of structural features of different molecules are proving to be more efficacious and safe in comparison to their individual counterparts.204
Keywords
ACTSMTBCC50GI50μMEC50μgMicrogramMIC50FerroquineFQAMICIC50BCGBPUGSTπglutathione S-transferase πSARCOX50% inhibitory concentrationBacillus Calmette-GuérindhfrROSTOPOcyclooxygenaseOleanolic acidLOXTuberculosisTopoisomeraseMinimum inhibitory concentrationdihydrofolate reductaseStructure activity relationshipWorld Health Organisationselectivity indexAnti-tubercularAnti-fungalAnti-malarialAnti-inflammatorylipoxygenaseMycobacterium tuberculosisHybrid moleculesmillimetremicromolarnanomolarNitric oxidehalf maximal effective concentrationChloroquineWHOReactive oxygen species
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shaveta Shaveta, Sahil Mishra, Palwinder Singh,