Article ID Journal Published Year Pages File Type
7797636 European Journal of Medicinal Chemistry 2016 11 Pages PDF
Abstract
Platinum complex with 9-amino-oxoisoaporphine is more selective to Hep-G2 cells versus HL-7702 cells, and its cytotoxicity mainly via inhibiting telomerase by interaction with c-myc quadruplex and disruption of mitochondrial function.207
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Stabilization of c-myc G-Quadruplex DNA, inhibition of telomerase activity, disruption of mitochondrial functions and tumor cell apoptosis by platinum(II) complex with 9-amino-oxoisoaporphine
Authors
, , , , , , , , ,