Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation

Article ID	Journal	Published Year	Pages	File Type
7797646	European Journal of Medicinal Chemistry	2016	51 Pages	PDF

Keywords

BTH MCF-7 AAPH HEK MIC TTC MSSA VRE EMEM acute lymphoblastic leukemia cells NDGA MIA PaCa-2 XTT HRBCs Human embryonic kidney 293 cells NCI-H460 SW620 L1210 2,3,5-triphenyl-2H-tetrazolium chloride MDR IC50 DOX FBS DMEM DPPH PBS CEM PSA (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 2,2-diphenyl-1-picrylhydrazyl radical DMSO Dulbecco's modified Eagle's medium MTT MRSA nordihydroguaiaretic acid Urea LOX Minimal inhibitory concentration Eagle's minimum essential medium Doxorubicin Dimethyl sulfoxide fetal bovine serum Breast carcinoma cells Cervical carcinoma cells Phosphate buffered saline Antioxidative activity Antiproliferative activity Antimicrobial activity VOR lipoxygenase Polar surface area VSE voriconazole Lipid peroxidation Primaquine Propidium iodide Hela Human red blood cells

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Novel urea and bis-urea primaquine derivatives with hydroxyphenyl or halogenphenyl substituents: Synthesis and biological evaluation

Authors

I. PerkoviÄ, M. AntunoviÄ, I. MarijanoviÄ, K. PaviÄ, K. Ester, M. Kralj, J. VlainiÄ, I. Kosalec, D. Schols, D. Hadjipavlou-Litina, E. Pontiki, B. Zorc,