Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing 1,2,4-triazolone moiety as c-Met kinase inhibitors

Article ID	Journal	Published Year	Pages	File Type
7797885	European Journal of Medicinal Chemistry	2016	16 Pages	PDF

Abstract

A series of novel 4-phenoxyquinoline derivatives containing 1,2,4-triazolone moiety were designed, synthesized and evaluated for their biological activities.147

Keywords

c-Met inhibitors 4-Phenoxyquinoline derivatives Synthesis Antitumor activity

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Preview

Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing 1,2,4-triazolone moiety as c-Met kinase inhibitors

Authors

Ju Liu, Minhua Nie, Yanjing Wang, Jinxing Hu, Feng Zhang, Yanlin Gao, Yajing Liu, Ping Gong,