| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7797893 | European Journal of Medicinal Chemistry | 2016 | 15 Pages |
Abstract
The most potent compound 9g shows absorbance in the near UV-Vis, a detectable activity as 1O2 sensitizer and photoinduced apoptosis with massive production of large amounts of ROS, and a deep involvement of mitochondria and lysosomes.74
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![Synthesis and antiproliferative mechanism of action of pyrrolo[3â²,2â²:6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers](/preview/png/7797893.png "First Page Preview: Synthesis and antiproliferative mechanism of action of pyrrolo[3â²,2â²:6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers")
Authors
Virginia Spanò, Ilaria Frasson, Daniele Giallombardo, Filippo Doria, Barbara Parrino, Anna Carbone, Alessandra Montalbano, Matteo Nadai, Patrizia Diana, Girolamo Cirrincione, Mauro Freccero, Sara N. Richter, Paola Barraja,