Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties

Article ID	Journal	Published Year	Pages	File Type
7797957	European Journal of Medicinal Chemistry	2016	73 Pages	PDF

Keywords

CLSI PYR MIC NADPH ACN IAEC CyP RBC 5-chloromethylfluorescein diacetate DOPG CMFDA MTB INH DMF PBS SAR MDR CFU DCCD dicyclohexylcarbodiimide DMSO Xanthone Adenosine Triphosphate ATP ethambutol eth MRSA methicillin-resistant Staphylococcus aureus Streptomycin Strep Acetonitrile isoniazid Osa Tuberculosis Minimum inhibitory concentration dimethylformamide Dimethyl sulfoxide Structure–activity relationship Rifampicin Cytochrome P450 Mass spectroscopy phosphate buffer saline lactate dehydrogenase LDH Mycobacteria Mycobacterium tuberculosis Multidrug-resistant nicotinamide adenine dinucleotide phosphate Membrane targeting human immunodeficiency virus HIV Pyrazinamide Cardiolipin Rif liquid chromatography colony forming unit institutional animal ethics committee red blood cell

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties

Authors

Jun-Jie Koh, Hanxun Zou, Devika Mukherjee, Shuimu Lin, Fanghui Lim, Javey Khiapeng Tan, Dhi-Zen Tan, Bridget L. Stocker, Mattie S.M. Timmer, Hilary M. Corkran, Rajamani Lakshminarayanan, Donald T.H. Tan, Derong Cao, Roger W. Beuerman, Thomas Dick,