New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties

Article ID	Journal	Published Year	Pages	File Type
7798302	European Journal of Medicinal Chemistry	2016	53 Pages	PDF

Keywords

SGZ Neuroprotectants MAOS βA BACE-1 beta-site amyloid precursor protein cleaving enzyme 1 NBP SH-SY5Y SVZ NMDA butyrylcholinesterase HSQC BuChE ORAC 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MTT ROS Antioxidants AChE Acetylcholinesterase Alzheimer’s disease oxygen radical absorbance capacity subgranular zone subventricular zone Monoamine oxidases HMBC یا Heteronuclear Multiple Bond Correlation heteronuclear multiple bond correlation Heteronuclear Single Quantum Correlation Beta-amyloid peptide Reactive oxygen species N-methyl-d-aspartate receptor

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties

Authors

MartÃn Estrada, Clara Herrera-Arozamena, Concepción Pérez, Dolores Viña, Alejandro Romero, José A. Morales-GarcÃa, Ana Pérez-Castillo, MarÃa Isabel RodrÃguez-Franco,