Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7798445 | European Journal of Medicinal Chemistry | 2016 | 51 Pages |
Abstract
A series of 3-O-β-chacotriosyl oleanolic acid analogs have been designed, synthesized and evaluated as H5N1 entry inhibitor, of which compound 8 showed the strongest inhibition activity with IC50 of 2.4 μM.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gaopeng Song, Xintian Shen, Sumei Li, Yibin Li, Hongzong Si, Jihong Fan, Junhua Li, Erqiang Gao, Shuwen Liu,