Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma

Article ID	Journal	Published Year	Pages	File Type
7798482	European Journal of Medicinal Chemistry	2016	17 Pages	PDF

Keywords

DMF DCM TFA TBTU N,N,N′,N′-tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate Oxindole derivatives N,N-dimethylformamide N,N-diisopropylethylamine Trifluoroacetic acid Dichloromethane Kinase inhibitors NAH DIPEA Sodium hydride Glioblastoma

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma

Authors

Simona Sestito, Simona Daniele, Giulia Nesi, Elisa Zappelli, Danilo Di Maio, Luciana Marinelli, Maria Digiacomo, Annalina Lapucci, Claudia Martini, Ettore Novellino, Simona Rapposelli,