| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7798584 | European Journal of Medicinal Chemistry | 2016 | 14 Pages |
Abstract
Systemic injection of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione (Compound 16), a novel potent d-amino acid oxidase (DAAO) inhibitor, inhibited formalin-induced tonic pain in rodents in a dose-dependent manner.189
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor](/preview/png/7798584.png "First Page Preview: Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor")
Authors
Dongsheng Xie, Jun Lu, Jin Xie, Junjun Cui, Teng-Fei Li, Yan-Chao Wang, Yuan Chen, Nian Gong, Xin-Yan Li, Lei Fu, Yong-Xiang Wang,