Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7798725 | European Journal of Medicinal Chemistry | 2016 | 11 Pages |
Abstract
Bioisosteric replacement of the phenol of potent GluN2B antagonists led to [7]annulenobenzimidazonoes. Intermediate tricyclic alcohol was prepared in a seven-step synthesis. Five additional steps provided phenylpropylamine showing moderate GluN2B affinity.91
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ines Lütnant, Dirk Schepmann, Bernhard Wünsch,