| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7799175 | European Journal of Medicinal Chemistry | 2015 | 20 Pages |
Abstract
A highly potent renin inhibitor 39 (IC50Â =Â 0.7Â nM), which may have additional interactions with the S3â² subsite of renin active site, has been identified by structural modification of aliskiren (1).
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Authors
Xiaowei Sun, Xiaoan Wen, Yan-yan Chen, Chen Shi, Chengzhe Gao, Yong Wu, Li-jun Wang, Xiu-hong Yang, Hongbin Sun,