Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

Article ID	Journal	Published Year	Pages	File Type
7799183	European Journal of Medicinal Chemistry	2015	72 Pages	PDF

Keywords

NF-κB DDIT4 HSP 90 GDF-15 CDKN1A RNR PI-3K CDK2 ARI FGF-2 Cytochromes P450 MCT HCA IC50 CDC CyP MMP SAR STS 50% inhibitory concentration dhfr hTERT ROS Steroid sulfatase Human carbonic anhydrase Targets human telomerase reverse transcriptase dihydrofolate reductase Structure activity relationship Ribonucleotide reductase CAM Synthesis Anticancer Growth differentiation factor 15 Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)nuclear factor-κB phosphatidylinositide 3-kinases fibroblast growth factor-2 matrix metalloproteinase cyclin-dependent kinase inhibitor 1A Aromatase inhibitor monocarboxylate transporter Heat shock protein 90 Coumarins cyclin dependent kinase 2 Reactive oxygen species

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Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

Authors

Anuradha Thakur, Ramit Singla, Vikas Jaitak,