Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study

Article ID	Journal	Published Year	Pages	File Type
7799332	European Journal of Medicinal Chemistry	2015	71 Pages	PDF

Keywords

G protein-coupled receptors Anti-nociceptive effect Allosteric modulator A1 adenosine receptor

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Preview

Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study

Authors

Romeo Romagnoli, Pier Giovanni Baraldi, Carlota Lopez-Cara, Olga Cruz-Lopez, Allan R. Moorman, Arnault Massink, Adriaan P. IJzerman, Fabrizio Vincenzi, Pier Andrea Borea, Katia Varani,