Preliminary research on 1-(4-bromo-2-nitroimidazol-1-yl)-3-[18F]fluoropropan-2-ol as a novel brain hypoxia PET tracer in a rodent model of stroke

Article ID	Journal	Published Year	Pages	File Type
7799431	European Journal of Medicinal Chemistry	2015	92 Pages	PDF

Keywords

FDG 2-fluoro-2-deoxy-D-glucose tetrahydropyranyl pyridinium p-toluenesulfonate N-bromophthalimide Tetrabutylammonium tetrafluoroborate 3,4-Dihydro-2H-pyran FMISO PPTS N-bromosuccinimide DHP FPN THP pMCAO NBS CBF 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MTT MRI SPECT PET imaging Magnetic resonance imaging single photon emission computed tomography computed tomography Positron emission tomography cerebral blood flow BBB Blood–brain barrier Stroke Fluorine-18 lactate dehydrogenase LDH Nitroimidazole Hypoxia PET optical density

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Preliminary research on 1-(4-bromo-2-nitroimidazol-1-yl)-3-[18F]fluoropropan-2-ol as a novel brain hypoxia PET tracer in a rodent model of stroke

Authors

Elena Nieto, Mercedes Delgado, Mónica Sobrado, MarÃa L. de Ceballos, Ramón AlajarÃn, Luis GarcÃa-GarcÃa, James Kelly, Ignacio Lizasoain, Miguel A. Pozo, Julio Álvarez-Builla,