Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7799465 | European Journal of Medicinal Chemistry | 2015 | 79 Pages |
Abstract
We synthesized a series of new 5-(2â²,4â²-difluorophenyl)-salicylanilide derivatives. Among them, 6d and 6i not only suppressed RANKL-induced NF-κB and NFATc1 activation, but also reduced expression levels of osteoclastogenesis-related genes.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chia-Chung Lee, Fei-Lan Liu, Chun-Liang Chen, Tsung-Chih Chen, Deh-Ming Chang, Hsu-Shan Huang,