Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7799497 | European Journal of Medicinal Chemistry | 2015 | 124 Pages |
Abstract
A meridianin sulfonamide derivative 14v showed promising antimalarial activity against D2 and W2 strains of Plasmodium falciparum, better than its parent natural product. The C-ring modified analog 12 exhibited potent anti-tubercular activity against sensitive as well as resistant Mtb strains with MIC of 2-8 μg/ml.
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Chemistry
Organic Chemistry
Authors
Rammohan R. Yadav, Shabana I. Khan, Samsher Singh, Inshad A. Khan, Ram A. Vishwakarma, Sandip B. Bharate,