Article ID Journal Published Year Pages File Type
7799497 European Journal of Medicinal Chemistry 2015 124 Pages PDF
Abstract
A meridianin sulfonamide derivative 14v showed promising antimalarial activity against D2 and W2 strains of Plasmodium falciparum, better than its parent natural product. The C-ring modified analog 12 exhibited potent anti-tubercular activity against sensitive as well as resistant Mtb strains with MIC of 2-8 μg/ml.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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