Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7799798 | European Journal of Medicinal Chemistry | 2015 | 36 Pages |
Abstract
A novel series of potent and efficacious factor Xa inhibitors which possesses pyrrole/indole/thiazole moieties as S4 binding element was identified. Compound 7b showed potent human factor Xa inhibitory activity.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yanfang Zhao, Mingyan Jiang, Shunguang Zhou, Shasha Wu, Xiaolong Zhang, Longsheng Ma, Kai Zhang, Ping Gong,