Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7799942 | European Journal of Medicinal Chemistry | 2015 | 9 Pages |
Abstract
A series of AChE/BuChE inhibitors namely 3-(4-(aminoalkoxy)benzylidene)-chroman-4-ones 7a-r were synthesized as homoisoflavonoid analogs. The obtained results revealed that compounds bearing piperidinylethoxy residue showed potent activity against AChE at sub-micromolar level.
Related Topics
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Organic Chemistry
Authors
Yaghoub Pourshojaei, Ali Gouranourimi, Shohre Hekmat, Ali Asadipour, Samira Rahmani-Nezhad, Alireza Moradi, Hamid Nadri, Farshad Homayouni Moghadam, Saeed Emami, Alireza Foroumadi, Abbas Shafiee,