PEGylation of the peptide Bac7(1-35) reduces renal clearance while retaining antibacterial activity and bacterial cell penetration capacity

Article ID	Journal	Published Year	Pages	File Type
7800064	European Journal of Medicinal Chemistry	2015	10 Pages	PDF

Keywords

CFU HCTU Et2O Phth Boc2O Ethyl ether PyBOP SPPS DIEA NMP SPB NCL RP-HPLC kiloDalton kDa CMC HRP PEGylation 2-Propanol N,N-diisopropylethylamine tris(2-carboxyethyl)phosphine hydrochloride sodium phosphate buffer Ion exchange Optical imaging Thioanisole Solid phase peptide synthesis phthaloyl Antibacterial activity Methanol MeOH Hydrazine hydrate Horseradish peroxidase Propidium iodide Proline-rich Antimicrobial peptide Pyridine Native chemical ligation Reversed phase high-performance liquid chromatography colony forming unit

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

PEGylation of the peptide Bac7(1-35) reduces renal clearance while retaining antibacterial activity and bacterial cell penetration capacity

Authors

Monica Benincasa, Sotir Zahariev, Chiara Pelillo, Annalisa Milan, Renato Gennaro, Marco Scocchi,