Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7800111 | European Journal of Medicinal Chemistry | 2015 | 11 Pages |
Abstract
A series of 2, 6-disubstituted pyridazinones were optimized for the c-Met activity. By an analysis of the SAR results, the quinoline-pyridazinone 8a was achieved as a selective c-Met inhibitor.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Weiqiang Xing, Jing Ai, Shiyu Jin, Zhangxing Shi, Xia Peng, Lang Wang, Yinchun Ji, Dong Lu, Yang Liu, Meiyu Geng, Youhong Hu,