| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7800144 | European Journal of Medicinal Chemistry | 2015 | 8 Pages |
Abstract
Mesothelioma cancer cells have been treated with histone deacetylase inhibitor CI-994-polymer conjugate showing restoration of HDAC inhibition correlated with cancer cells apoptosis.
Keywords
PDIpentamethyldiethylenetriamineadcAPMDETAROMPfluorescein-isothiocyanateMBUTSGMPMHDACiDDSBRDHDACTLCTHFDLSSECFITCDMFPTMNPsAdenocarcinomaControlled releasebioluminescence resonance energy transferPolyethylene oxideBRETBromodomainTetrahydrofuranDrug deliverypost-translational modificationsdimethyl formamideDrug delivery systempolydispersity indexStimuli-responsiveMalignant pleural mesotheliomahistone deacetylase inhibitorNanoparticlesPolymeric nanoparticleNorbornenehistone deacetylasesDynamic Light ScatteringRing-opening metathesis polymerizationPEOTumor Suppressor GenesSize exclusion chromatographythin layer chromatography
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Iza Denis, Fatima el Bahhaj, Floraine Collette, Régis Delatouche, Fabien Gueugnon, Daniel Pouliquen, Loic Pichavant, Valérie Héroguez, Marc Grégoire, Philippe Bertrand, Christophe Blanquart,