| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7800162 | European Journal of Medicinal Chemistry | 2015 | 15 Pages |
Abstract
Novel quinazolinone hybrids were designed and synthesized for activation of p53 and its dependent genes p21 and p16 by the inhibition of HDACs, resulted in growth arrest of cervical cancer cells and changes in expression of key proteins, leading to senescence.
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Authors
Ramineni Venkatesh, M. Janaki Ramaiah, Hanmant K. Gaikwad, Sridhara Janardhan, Rajashaker Bantu, Lingaiah Nagarapu, G. Narahari Sastry, A. Raksha Ganesh, Manikapal Bhadra,