| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7800174 | European Journal of Medicinal Chemistry | 2015 | 18 Pages |
Abstract
A series of novel piperazine-thioureas-UA derivatives (6-7) was designed and synthesized as antitumor agents. Representative compound 6r blocked the HeG2 cell cycle at G1 phase and induced apoptosis of this cell through mitochondrial pathway.
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Authors
Shi-Xian Hua, Ri-Zhen Huang, Man-Yi Ye, Ying-Ming Pan, Gui-Yang Yao, Ye Zhang, Heng-Shan Wang,