Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7800265 | European Journal of Medicinal Chemistry | 2015 | 8 Pages |
Abstract
Novel celastrol derivatives as potential telomerase inhibitors were designed and synthesized. Compound 3c exhibited strong inhibitory activity against SMMC-7721 cells, and showed the most potent telomerase inhibitory activity.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Wen-Jian Tang, Jing Wang, Xu Tong, Jing-Bo Shi, Xin-Hua Liu, Jun Li,