| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7800420 | European Journal of Medicinal Chemistry | 2014 | 69 Pages |
Abstract
The efficient synthesis and ring fusion into anthra[2,3-d]oxazole-2-thione-5,10-diones were developed. Four compounds were selected by NCI and three compounds for topoisomerase I-mediated DNA relaxation.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Ring fusion strategy for the synthesis of anthra[2,3-d]oxazole-2-thione-5,10-dione homologues as DNA topoisomerase inhibitors and as antitumor agents](/preview/png/7800420.png "First Page Preview: Ring fusion strategy for the synthesis of anthra[2,3-d]oxazole-2-thione-5,10-dione homologues as DNA topoisomerase inhibitors and as antitumor agents")
Authors
Chun-Liang Chen, Fei-Lan Liu, Chia-Chung Lee, Tsung-Chih Chen, Wen-Wei Chang, Jih-Hwa Guh, Ahmed Atef Ahmed Ali, Deh-Ming Chang, Hsu-Shan Huang,