Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7800425 | European Journal of Medicinal Chemistry | 2014 | 13 Pages |
Abstract
A series of imidazole styrylindoles and sulfonyl styrylindoles derivatives were prepared and evaluated for their binding affinity and inhibitory activity against CYP24A1 with molecular modelling studies to determine key binding interactions within the CYP24A1 active site.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Salvatore Ferla, Mohamed S. Gomaa, Andrea Brancale, Jinge Zhu, Justin T. Ochalek, Hector F. DeLuca, Claire Simons,