| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7800594 | European Journal of Medicinal Chemistry | 2014 | 58 Pages |
Abstract
By fragment screening and x-ray crystallography techniques a scaffold of 4,5-diarylisoxazole was selected and developed to a novel series of HSP90 inhibitors with excellent in vivo activities.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Danqi Chen, Aijun Shen, Jian Li, Feng Shi, Wuyan Chen, Jing Ren, Hongchun Liu, Yechun Xu, Xin Wang, Xinying Yang, Yiming Sun, Min Yang, Jianhua He, Yueqin Wang, Liping Zhang, Min Huang, Meiyu Geng, Bing Xiong, Jingkang Shen,