Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI

Article ID	Journal	Published Year	Pages	File Type
7800609	European Journal of Medicinal Chemistry	2014	19 Pages	PDF

Keywords

MION LRMS Pittsburgh compound-B IMPY Fluorodesoxyglucose HBTU DIEA DOTA Th-T N-hydroxysuccinimide CMC PiB HOBt NHS HEPES FDG BAT Stilbene ICP-AES 1-hydroxybenzotriazole 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid USPIO N,N-diisopropylethylamine Longitudinal relaxivity Amyloid mild cognitive impairment Magnetic Resonance Imaging (MRI)BtA Alzheimer's disease Thioflavin-T Spin–lattice relaxation time spin–spin relaxation time inductively coupled plasma-atomic emission spectroscopy Inductively coupled plasma-mass spectroscopy ICP-MS Contrast agent Mama MCI Gadolinium

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Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI

Authors

Guillaume Bort, Sarah Catoen, HélÃ¨ne Borderies, Adel Kebsi, Sébastien Ballet, Gaëlle Louin, Marc Port, Clotilde Ferroud,