Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents

Article ID	Journal	Published Year	Pages	File Type
7800650	European Journal of Medicinal Chemistry	2014	14 Pages	PDF

Keywords

COX-2 AGEs HNE ARI DHN Advanced glycation-end products 1,4-dihydroxynonene GS-HNE Aldose reductase Diabetes mellitus Cyclooxygenase-2 Anti-inflammatory agents Molecular modelling Aldose reductase inhibitor Enzyme inhibitors

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Preview

Structure-activity relationships and molecular modelling of new 5-arylidene-4-thiazolidinone derivatives as aldose reductase inhibitors and potential anti-inflammatory agents

Authors

Rosanna Maccari, Rosa Maria Vitale, Rosaria OttanÃ , Marco Rocchiccioli, Agostino Marrazzo, Venera Cardile, Adriana Carol Eleonora Graziano, Pietro Amodeo, Umberto Mura, Antonella Del Corso,