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Synthesis, crystal structure and antiproliferative activity of Cu(II) nalidixic acid-DACH conjugate: Comparative in vitro DNA/RNA binding profile, cleavage activity and molecular docking studies

Article ID Journal Published Year Pages File Type
7800671 European Journal of Medicinal Chemistry 2014 52 Pages PDF
Abstract
Targeting DNA and RNA by molecular docking studies.
Keywords
U2OS cellsTopoisomerase IIU2OSpBR322 DNA cleavageCt-DNACalf thymus DNAUV–visibleUV–Visnalidixic acidTopo IIMolecular docking studies
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Synthesis, crystal structure and antiproliferative activity of Cu(II) nalidixic acid-DACH conjugate: Comparative in vitro DNA/RNA binding profile, cleavage activity and molecular docking studies
Authors
Farukh Arjmand, Imtiyaz Yousuf, Taibi ben Hadda, Loic Toupet,
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Journal
European Journal of Medicinal Chemistry
Journal: European Journal of Medicinal Chemistry
Related Categories
U2OS cells
Topoisomerase II
U2OS
pBR322 DNA cleavage
Ct-DNA
Calf thymus DNA
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UV–Vis
nalidixic acid
Topo II
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