Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7800820 | European Journal of Medicinal Chemistry | 2014 | 53 Pages |
Abstract
The design and synthesis of new hybrid architecture in the search of novel antifilarial agents is described. Compound 4n: IC50 = 0.9 μM (for adult worms assessed by motility assay). Ivermectin: IC50 = 3.05 μM (for adult worms assessed by motility assay).
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Authors
Koneni V. Sashidhara, K. Bhaskara Rao, Vikas Kushwaha, Ram K. Modukuri, Richa Verma, P.K. Murthy,