| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7801017 | European Journal of Medicinal Chemistry | 2014 | 12 Pages |
Abstract
Zinc complexes with the non-steroidal anti-inflammatory drug tolfenamic acid show significant antioxidant activity and pronounced binding behaviour towards DNA and serum albumins compared to the free drug.
Keywords
NDGAethidium bromide, 3,8-diamino-5-ethyl-6-phenyl-phenanthridinium bromideDMFHSANSAIDABTSBHTDPPHCOX1,10-Phenanthroline2,2′-BipyridineBSADMSODPPH radical scavenging activityN,N-dimethylformamideSerum albuminhuman serum albuminbovine serum albumintolfenamic acidnordihydroguaiaretic acidLOXInteraction with calf-thymus DNAInteraction with serum albuminsbipyDimethylsulfoxidecyclo-oxygenaseNon-steroidal anti-inflammatory drugAntioxidant activityPhenSoybean lipoxygenaseZinc(II) complexesbutylated hydroxytoluenecalf-thymus
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Antioxidant activity and interaction with DNA and albumins of zinc-tolfenamato complexes. Crystal structure of [Zn(tolfenamato)2(2,2â²-dipyridylketoneoxime)2]](/preview/png/7801017.png "First Page Preview: Antioxidant activity and interaction with DNA and albumins of zinc-tolfenamato complexes. Crystal structure of [Zn(tolfenamato)2(2,2â²-dipyridylketoneoxime)2]")
Authors
Alketa Tarushi, Xanthippi Totta, Athanasios Papadopoulos, Jakob Kljun, Iztok Turel, Dimitris P. Kessissoglou, George Psomas,