Article ID Journal Published Year Pages File Type
7801219 European Journal of Medicinal Chemistry 2014 11 Pages PDF
Abstract
Synthesis, characterization, DNA binding, cleavage and topoisomerase I inhibition activity of [Co(mpca)2]·H2O (1) was investigated. Complex recognizes minor groove and cleave DNA via hydrolytic pathway.
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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Synthesis and structure elucidation of a cobalt(II) complex as topoisomerase I inhibitor: In vitro DNA binding, nuclease and RBC hemolysis
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