Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7801290 | European Journal of Medicinal Chemistry | 2013 | 12 Pages |
Abstract
A series of diarylureas and diarylamides possessing 4-aryl-8-amino(acetamido)quinoline scaffold was synthesized. Their in vitro antiproliferative activities against ten melanoma cell lines, MEK/ERK kinase inhibition, and in silico studies are reported.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Eun Jeong Koh, Mohammed I. El-Gamal, Chang-Hyun Oh, So Ha Lee, Taebo Sim, Garam Kim, Hong Seok Choi, Jun Hee Hong, Sang-gi Lee, Kyung Ho Yoo,