| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7801585 | European Journal of Medicinal Chemistry | 2013 | 11 Pages |
Abstract
3-(Trimethoxyphenyl)-2(3H)-thiazole-thiones 5 and related compounds were synthesized as new heterocyclic analogs of CA-4. Representatively, compound 5f (RÂ =Â 4-Me) depolymerized tubulin, inhibited cell proliferation, and induced apoptosis in cancer cells.
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Authors
Mandana Banimustafa, Asma Kheirollahi, Maliheh Safavi, Sussan Kabudanian Ardestani, Hassan Aryapour, Alireza Foroumadi, Saeed Emami,