Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Article ID	Journal	Published Year	Pages	File Type
7801603	European Journal of Medicinal Chemistry	2013	10 Pages	PDF

Keywords

LRRK2 BMK1 Pd2(dba)3 DIEA DMA ERK5 MEK5 EGF HCC MAPK N,N-Dimethylacetamide N,N-diisopropylethylamine Kinase selectivity epidermal growth factor mitogen-activated protein kinase Hepatocellular carcinoma leucine rich repeat kinase 2

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Authors

Xianming Deng, Jonathan M. Elkins, Jinwei Zhang, Qingkai Yang, Tatiana Erazo, Nestor Gomez, Hwan Geun Choi, Jinhua Wang, Nicolas Dzamko, Jiing-Dwan Lee, Taebo Sim, NamDoo Kim, Dario R. Alessi, Jose M. Lizcano, Stefan Knapp, Nathanael S. Gray,