Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802138 | European Journal of Medicinal Chemistry | 2013 | 9 Pages |
Abstract
Compounds 8a-u were synthesized. 8f, 8m and 8q showed broad spectrum antiproliferative activity and induced DNA damage in HCT-116 cells, leading to the G2/M checkpoint activation and G2/M arrest.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sheng-Li Cao, Ying Han, Chong-Zhen Yuan, Yao Wang, Zhi-Kai Xiahou, Ji Liao, Rui-Ting Gao, Bei-Bei Mao, Bao-Li Zhao, Zhong-Feng Li, Xingzhi Xu,