Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802222 | European Journal of Medicinal Chemistry | 2013 | 6 Pages |
Abstract
Two efficient syntheses of 7α-testosterone-chlorambucil hybrid (1) are reported. MTT assays showed that the hybrid is selective towards hormone-dependent prostate cancer cell line (LNCaP) and is as active as chlorambucil.
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Authors
Dominic Bastien, Rana Hanna, Valérie Leblanc, Ãric Asselin, Gervais Bérubé,