Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802227 | European Journal of Medicinal Chemistry | 2013 | 7 Pages |
Abstract
A series of triazole antifungal derivatives were designed and synthesized by heterocycle-benzene bioisosteric replacement. The target compounds showed good antifungal activity toward a wide range of pathogenic fungi with improved pharmacokinetic profile.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhigan Jiang, Yan Wang, Wenya Wang, Shengzheng Wang, Bo Xu, Guorong Fan, Guoqiang Dong, Yang Liu, Jianzhong Yao, Zhenyuan Miao, Wannian Zhang, Chunquan Sheng,