| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802298 | European Journal of Medicinal Chemistry | 2012 | 11 Pages |
Abstract
⺠A series of 34 novel compounds were prepared and chemically characterized. ⺠The compounds were evaluated for their ALK5 inhibitory activity in enzyme assay and in cell-based luciferase reporter assay. ⺠Compounds 12b and 12g exhibited highly potent ALK5 inhibitory activity and selectivity indices of >400 over p38α MAP kinase.
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Authors
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