| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802349 | European Journal of Medicinal Chemistry | 2012 | 9 Pages |
Abstract
⺠Synthesis of all mono isopentenyloxy, -geranyloxy and -farnesyloxy coumarins. ⺠Assay of the inhibitory potency (IC50) against soybean and human 15-lipoxygenase. ⺠Determination of the inhibitory mechanism. âºÂ Docking analysis on both soybean and human 15-lipoxygenase. âºÂ Discussion about IC50 differences between the human and plant enzyme.
Related Topics
Physical Sciences and Engineering
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Authors
Mehrdad Iranshahi, Atena Jabbari, Ala Orafaie, Robabeh Mehri, Soudabeh Zeraatkar, Taraneh Ahmadi, Maliheh Alimardani, Hamid Sadeghian,