Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802371 | European Journal of Medicinal Chemistry | 2012 | 9 Pages |
Abstract
⺠A series of pyrazolo[4,3-c]cinnoline derivatives were synthesized. ⺠Characterized by IR, 1H NMR, 13C NMR, and DART-MASS technique. ⺠Anti-inflammatory, ulcerogenic, lipid peroxidation, COX-2 inhibition and antibacterial studies were performed. ⺠Compounds 4d and 4l showed excellent protection against inflammation. ⺠Compound 4b emerged as a potential dual anti-inflammatory-antibacterial agent.
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rajiv Kumar Tonk, Sandhya Bawa, Gita Chawla, Girdhar Singh Deora, Suresh Kumar, Vandana Rathore, Naveen Mulakayala, Azad Rajaram, Arunasree M. Kalle, Obaid Afzal,