Article ID Journal Published Year Pages File Type
7802371 European Journal of Medicinal Chemistry 2012 9 Pages PDF
Abstract
► A series of pyrazolo[4,3-c]cinnoline derivatives were synthesized. ► Characterized by IR, 1H NMR, 13C NMR, and DART-MASS technique. ► Anti-inflammatory, ulcerogenic, lipid peroxidation, COX-2 inhibition and antibacterial studies were performed. ► Compounds 4d and 4l showed excellent protection against inflammation. ► Compound 4b emerged as a potential dual anti-inflammatory-antibacterial agent.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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