| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802389 | European Journal of Medicinal Chemistry | 2012 | 8 Pages |
Abstract
⺠A series of bezafibrate ester prodrugs were synthesized. ⺠Synthesized compounds were evaluated for in vivo hypolipidemic activity. ⺠Prodrug 7 emerged as new potent hypolipidemic agent.
Keywords
PPAR-αBDLSAMHDLCPSDVLDLAPIdimethylacetamideLDLcDMACarylperoxisome proliferator-activated receptor alphacoronary artery diseasestriglycerideParticle size distributionstandard errorPhysicochemical propertiesRetention timeCADHypolipidemic activityvery-low-density lipoproteinhigh-density lipoprotein cholesterolbelow detection limitActive Pharmaceutical IngredientSwiss albino miceProdrugshigh performance liquid chromatographyHPLCgas chromatographtotal cholesterol
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Babasaheb P. Bandgar, Rajendra J. Sarangdhar, Khan Fruthous, Jeyamurugan Mookkan, Shilpee Chaudhary, Hemant V. Chavan, Sunil B. Bandgar, Vinayak Y. Kshirsagar,