| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802417 | European Journal of Medicinal Chemistry | 2012 | 15 Pages |
Abstract
⺠Synthesis of forty carboline derivatives and their structural elucidation. ⺠Using molecular modelling, ensemble docking to decide about the status of the H-loop of PDE5. ⺠Some compounds were as active as tadalafil and with better selectivity profile.
Related Topics
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Organic Chemistry
Authors
Nermin S. Ahmed, Amal H. Ali, Shreen M. El-Nashar, Bernard D. Gary, Alexandra M. Fajardo, Heather N. Tinsley, Gary A. Piazza, Matthias Negri, Ashraf H. Abadi,