Article ID Journal Published Year Pages File Type
7802423 European Journal of Medicinal Chemistry 2012 10 Pages PDF
Abstract
► 30 acylhydrazone derivatives have been synthesized. ► Their biological activities were evaluated as potential antibacterial and selective FabH inhibitors for the first time. ► Compound E9 showed the most potent FabH inhibition.
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Design, synthesis and antibacterial activities of vanillic acylhydrazone derivatives as potential β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitors
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