| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802430 | European Journal of Medicinal Chemistry | 2012 | 10 Pages |
Abstract
⺠A novel series of triazolothiadiazines were synthesized. ⺠Compounds were screened for their cytotoxicity using MTT assay. ⺠Compounds also tested for their anthelmintic & antimicrobial activities. ⺠7j was the most promising cytotoxic agent with IC50 value of 10.54 μM in MCF-7 cells.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pushpan Puthiyapurayil, Boja Poojary, Chandrashekhar Chikkanna, Sunil Kumar Buridipad,
![First Page Preview: Synthesis, spectral characterization and biological evaluation of a novel series of 6-arylsubstituted-3-[2-(4-substitutedphenyl)propan-2-yl]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines Synthesis, spectral characterization and biological evaluation of a novel series of 6-arylsubstituted-3-[2-(4-substitutedphenyl)propan-2-yl]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines](/preview/png/7802430.png)