| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802497 | European Journal of Medicinal Chemistry | 2012 | 6 Pages |
Abstract
⺠New 4-benzylidenehydrazinyl-pyrazolo[3,4-d]pyrimidines 6a-p were synthesized. ⺠The cytotoxic activity of the synthesized compounds against MCF7 was investigated. ⺠The compounds showed potent antitumor activity comparable to that of doxorubicin. ⺠Compound 6d was the most active compound with IC50 equal to 7.5 nM.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
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Authors
Mohammed K. Abd El Hamid, Marko D. Mihovilovic, Hala B. El-Nassan,