| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802537 | European Journal of Medicinal Chemistry | 2012 | 9 Pages |
Abstract
⺠A series of pyridazines were prepared and evaluated for their antiviral activity. ⺠Most of these compounds possess anti-HIV activity and anti-TMV activity. ⺠The rearranged compounds 35 and 39 exhibited higher HIV inhibitory effect. ⺠Compound 9 showed similar in vivo anti-TMV activity to commercial Ribavirin. ⺠An efficient approach to evolve novel multi-functional antiviral agents was described.
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Authors
Ziwen Wang, Mingxiao Wang, Xue Yao, Yue Li, Juan Tan, Lizhong Wang, Wentao Qiao, Yunqi Geng, Yuxiu Liu, Qingmin Wang,