Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802538 | European Journal of Medicinal Chemistry | 2012 | 7 Pages |
Abstract
⺠A series of novel indolylquinone derivatives were synthesized by a mild method. ⺠The compounds were tested in vitro on MDA-MB-231 and MCF-7 breast cancer cell. ⺠The compounds are novel with decent cytotoxic activities. ⺠3d and 3g displayed the most potent antiproliferative activity of the series. ⺠They inhibited breast cancer cells proliferation by triggering apoptotic cell death.
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Authors
Xue Li, Shi-Long Zheng, Xian Li, Ju-Lian Li, Ou Qiang, Rui Liu, Ling He,